San Francisco 49ers: 2021 NFL Schedule
Below you will find the weekly regular-season schedule for the San Francisco 49ers.
| Week | Date | Opponent | Results |
|---|---|---|---|
| Week 1 | Sun., Sept. 12 | at Detroit Lions | W 41-33 |
| Week 2 | Sun., Sept. 19 | at Philadelphia Eagles | W 17-11 |
| Week 3 | Sun., Sept. 26 | vs. Green Bay Packers | L 28-30 |
| Week 4 | Sun., Oct. 3 | vs. Seattle Seahawks | L 21-28 |
| Week 5 | Sun., Oct. 10 | at Arizona Cardinals | L 10-17 |
| Week 6 | BYE | ||
| Week 7 | Sun., Oct. 24 | vs. Indianapolis Colts | L 18-30 |
| Week 8 | Sun., Oct. 31 | at Chicago Bears | W 33-22 |
| Week 9 | Sun., Nov. 7 | vs. Arizona Cardinals | L 17-31 |
| Week 10 | Mon., Nov. 15 | vs. Los Angeles Rams | W 31-10 |
| Week 11 | Sun., Nov. 21 | at Jacksonville Jaguars | W 30-10 |
| Week 12 | Sun., Nov. 28 | vs. Minnesota Vikings | W 34-26 |
| Week 13 | Sun., Dec. 5 | at Seattle Seahawks | L 23-30 |
| Week 14 | Sun., Dec. 12 | at Cincinnati Bengals | W 26-23 (OT) |
| Week 15 | Sun., Dec. 19 | vs. Atlanta Falcons | W 31-13 |
| Week 16 | Thu., Dec. 23 | at Tennessee Titans | L 17-20 |
| Week 17 | Sun., Jan. 2 | vs. Houston Texans | W 23-7 |
| Week 18 | Sun., Jan. 9 | at Los Angeles Rams | W 27-24 (OT) |
NFL Playoffs Schedule
| Week | Date | Opponent | Results |
|---|---|---|---|
| WC Round | Sun., Jan. 16 | at Dallas Cowboys | W 23-17 |
| Div. Round | Sat., Jan. 22 | at Green Bay Packers | W 13-10 |
| NFC Championship | Sun., Jan. 30 | at Los Angeles Rams | L 17-20 |
Past 49ers results: 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010
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