Detroit Lions: 2022 NFL Schedule
Below you will find the weekly regular-season schedule for the Detroit Lions.
| Week | Date | Opponent | Time (ET) / Tickets |
| Week 1 | Sun., Sept. 11 | vs. Philadelphia Eagles | 1:00 PM / Tickets |
| Week 2 | Sun., Sept. 18 | vs. Washington Commanders | 1:00 PM / Tickets |
| Week 3 | Sun., Sept. 25 | at Minnesota Vikings | 1:00 PM / Tickets |
| Week 4 | Sun., Oct. 2 | vs. Seattle Seahawks | 1:00 PM / Tickets |
| Week 5 | Sun., Oct. 9 | at New England Patriots | 1:00 PM / Tickets |
| Week 6 | | BYE | |
| Week 7 | Sun., Oct. 23 | at Dallas Cowboys | 1:00 PM / Tickets |
| Week 8 | Sun., Oct. 30 | vs. Miami Dolphins | 1:00 PM / Tickets |
| Week 9 | Sun., Nov. 6 | vs. Green Bay Packers | 1:00 PM / Tickets |
| Week 10 | Sun., Nov. 13 | at Chicago Bears | 1:00 PM / Tickets |
| Week 11 | Sun., Nov. 20 | at New York Giants | 1:00 PM / Tickets |
| Week 12 | Thu., Nov. 24 | vs. Buffalo Bills | 12:45 PM / Tickets |
| Week 13 | Sun., Dec. 4 | vs. Jacksonville Jaguars | 1:00 PM / Tickets |
| Week 14 | Sun., Dec. 11 | vs. Minnesota Vikings | 1:00 PM / Tickets |
| Week 15 | Sun., Dec. 18 | at New York Jets | 1:00 PM / Tickets |
| Week 16 | Sat. Dec. 24 | at Carolina Panthers | 1:00 PM / Tickets |
| Week 17 | Sun., Jan. 1 | vs. Chicago Bears | 1:00 PM / Tickets |
| Week 18 | Jan. 7 or Jan. 8 | at Green Bay Packers | TBD / Tickets |
Past Lions results: 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010
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